目的 探讨硫磺熏蒸在党参药材储藏过程中的利与弊。方法 二氧化硫残留量采用蒸馏法进行测定;药材性状参照药典进行考察;采用紫外分光光度法测定党参多糖含量,采用高效液相色谱法对党参炔苷和苍术内酯Ⅲ的含量进行测定,并建立特征指纹图谱。结果 党参药材在自然条件下贮藏,其性状质量和代表有效组分随贮藏时间的延长而持续降低。储藏至30个月,未熏硫样品颜色变深、虫蛀严重,党参多糖、党参炔苷和苍术内酯Ⅲ的含量降低一半以上,并检出黄曲霉毒素;熏硫样品仅个别出现虫蛀现象,党参多糖、党参炔苷和苍术内酯Ⅲ含量均显著降低,但降低幅度显著低于未熏硫样品。结论 贮藏时间和党参药材质量呈负相关,适度熏硫可有效的减缓党参品质下降的速率。
Abstract
OBJECTIVE To investigate the advantages and disadvantages of sulfuring to Codonopsis Radix in its process of storage. METHODS Sulfur dioxide residual amount was determined by distillation. The character was observed referring to Ch.P. The content of polysaccharide was measured by ultraviolet spectrophotometry. The contents of lobetyolin and rhizome atractylodis inner fat Ⅲ were measured by high performance liquid chromatography, and fingerprints were established. RESULTS Under the natural storage conditions, the contents of effective components decreased with the extension of storage time. After being stored for 30 m, the Codonopsis Radix samples without sulfuring treatment had darkened color and were damaged by worms seriously,the contents of polysaccharide,lobetyolin, and rhizome atractylodis inner fat Ⅲ reduced by more than half, and yellow aspergillus toxin were detected; however, few sulfured samples were damaged by worms and the magnitude of content decrease of the three compounds was significantly smaller than that of the non-sulfured ones. CONCLUSION Storage time is negatively correlated with the medicinal quality of Codonopsis Radix and proper sulfuring can slow the rate of quality deteriorating of Codonopsis Radix.
关键词
党参 /
二氧化硫 /
党参多糖 /
党参炔苷 /
苍术内酯Ⅲ
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Key words
Codonopsis Radix /
sulfur dioxide /
polysaccharide /
lobetyolin /
rhizome atractylodis inner fat Ⅲ
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中图分类号：
R282
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参考文献
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脚注
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基金
国家自然科学基金资助项目(81360622);遵义医学院博士科研启动资金资助项目(F-805);甘肃省自然科学基金资助项目(1107RJZA210);甘肃省省属普通本科高校基本科研业务费专项资金资助(甘财教[2014]63号-5);兰州市2014年人才创新创业专项资助(2014-2-15)
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